Ultra-Rapid Glutathionylation of Ribonuclease: Is This the Real Incipit of Its Oxidative Folding?

Many details of oxidative folding of proteins remain obscure, in particular, the role of oxidized glutathione (GSSG). This study reveals some unknown aspects. When a reduced ribonuclease A refolds in the presence of GSSG, most of its eight cysteines accomplish a very fast glutathionylation. In parti...

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Detalles Bibliográficos
Autores principales: Bocedi, Alessio, Cattani, Giada, Gambardella, Giorgia, Ticconi, Silvia, Cozzolino, Flora, Di Fusco, Ornella, Pucci, Piero, Ricci, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862303/
https://www.ncbi.nlm.nih.gov/pubmed/31683668
http://dx.doi.org/10.3390/ijms20215440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862303/
https://www.ncbi.nlm.nih.gov/pubmed/31683668
http://dx.doi.org/10.3390/ijms20215440

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