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DPP9’s Enzymatic Activity and Not Its Binding to CARD8 Inhibits Inflammasome Activation
[Image: see text] Inflammasomes are multiprotein complexes formed in response to pathogens. NLRP1 and CARD8 are related proteins that form inflammasomes, but the pathogen-associated signal(s) and the molecular mechanisms controlling their activation have not been established. Inhibitors of the serin...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862324/ https://www.ncbi.nlm.nih.gov/pubmed/31525884 http://dx.doi.org/10.1021/acschembio.9b00462 |