Hydroa Vacciniforme-Like Lymphoma with Systemic Symptoms: Two Case Reports

Two Chinese children presented with relapsing papules, vesicles, ulcers on the face and limbs with systemic symptoms being caused by mosquito bite. Lesion biopsy revealed atypical lymphocyte in the dermis and subcutis. Immunohistochemistry identified cells as positive for CD3, CD45RO, TIA-1 and EBER...

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Detalles Bibliográficos
Autores principales: Wang, Litao, Su, Yuwen, Zhang, Jianzhong, Wen, Haiquan, Zhang, Guiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862358/
https://www.ncbi.nlm.nih.gov/pubmed/31896851
http://dx.doi.org/10.4103/ijd.IJD_178_18
Descripción
Sumario:Two Chinese children presented with relapsing papules, vesicles, ulcers on the face and limbs with systemic symptoms being caused by mosquito bite. Lesion biopsy revealed atypical lymphocyte in the dermis and subcutis. Immunohistochemistry identified cells as positive for CD3, CD45RO, TIA-1 and EBER. Taken together, both the patients were diagnosed with hydroa vacciniforme-like lymphoma. Two patients showed significant improvement in clinical symptoms after being treated with acyclovir, low dose predisone and IFN-α.

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