Hydroa Vacciniforme-Like Lymphoma with Systemic Symptoms: Two Case Reports

Two Chinese children presented with relapsing papules, vesicles, ulcers on the face and limbs with systemic symptoms being caused by mosquito bite. Lesion biopsy revealed atypical lymphocyte in the dermis and subcutis. Immunohistochemistry identified cells as positive for CD3, CD45RO, TIA-1 and EBER...

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Autores principales: Wang, Litao, Su, Yuwen, Zhang, Jianzhong, Wen, Haiquan, Zhang, Guiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862358/
https://www.ncbi.nlm.nih.gov/pubmed/31896851
http://dx.doi.org/10.4103/ijd.IJD_178_18
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author Wang, Litao
Su, Yuwen
Zhang, Jianzhong
Wen, Haiquan
Zhang, Guiying
author_facet Wang, Litao
Su, Yuwen
Zhang, Jianzhong
Wen, Haiquan
Zhang, Guiying
author_sort Wang, Litao
collection PubMed
description Two Chinese children presented with relapsing papules, vesicles, ulcers on the face and limbs with systemic symptoms being caused by mosquito bite. Lesion biopsy revealed atypical lymphocyte in the dermis and subcutis. Immunohistochemistry identified cells as positive for CD3, CD45RO, TIA-1 and EBER. Taken together, both the patients were diagnosed with hydroa vacciniforme-like lymphoma. Two patients showed significant improvement in clinical symptoms after being treated with acyclovir, low dose predisone and IFN-α.
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spelling pubmed-68623582020-01-02 Hydroa Vacciniforme-Like Lymphoma with Systemic Symptoms: Two Case Reports Wang, Litao Su, Yuwen Zhang, Jianzhong Wen, Haiquan Zhang, Guiying Indian J Dermatol Case Report Two Chinese children presented with relapsing papules, vesicles, ulcers on the face and limbs with systemic symptoms being caused by mosquito bite. Lesion biopsy revealed atypical lymphocyte in the dermis and subcutis. Immunohistochemistry identified cells as positive for CD3, CD45RO, TIA-1 and EBER. Taken together, both the patients were diagnosed with hydroa vacciniforme-like lymphoma. Two patients showed significant improvement in clinical symptoms after being treated with acyclovir, low dose predisone and IFN-α. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6862358/ /pubmed/31896851 http://dx.doi.org/10.4103/ijd.IJD_178_18 Text en Copyright: © 2019 Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Wang, Litao
Su, Yuwen
Zhang, Jianzhong
Wen, Haiquan
Zhang, Guiying
Hydroa Vacciniforme-Like Lymphoma with Systemic Symptoms: Two Case Reports
title Hydroa Vacciniforme-Like Lymphoma with Systemic Symptoms: Two Case Reports
title_full Hydroa Vacciniforme-Like Lymphoma with Systemic Symptoms: Two Case Reports
title_fullStr Hydroa Vacciniforme-Like Lymphoma with Systemic Symptoms: Two Case Reports
title_full_unstemmed Hydroa Vacciniforme-Like Lymphoma with Systemic Symptoms: Two Case Reports
title_short Hydroa Vacciniforme-Like Lymphoma with Systemic Symptoms: Two Case Reports
title_sort hydroa vacciniforme-like lymphoma with systemic symptoms: two case reports
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862358/
https://www.ncbi.nlm.nih.gov/pubmed/31896851
http://dx.doi.org/10.4103/ijd.IJD_178_18
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AT wenhaiquan hydroavacciniformelikelymphomawithsystemicsymptomstwocasereports
AT zhangguiying hydroavacciniformelikelymphomawithsystemicsymptomstwocasereports

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