Transdermal delivery of 4-aminopyridine accelerates motor functional recovery and improves nerve morphology following sciatic nerve crush injury in mice

Oral 4-aminopyridine (4-AP) is clinically used for symptomatic relief in multiple sclerosis and we recently demonstrated that systemic 4-AP had previously unknown clinically-relevant effects after traumatic peripheral nerve injury including the promotion of re-myelination, improvement of nerve condu...

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Detalles Bibliográficos
Autores principales: Clark, Andrew R., Hsu, Chia George, Talukder, M A Hassan, Noble, Mark, Elfar, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862422/
https://www.ncbi.nlm.nih.gov/pubmed/31535662
http://dx.doi.org/10.4103/1673-5374.264471

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