Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that exert important functions in mediating the pleiotropic effects of diverse exogenous factors such as physical exercise and food components. Particularly, PPARs act as transcription factors that control the expression of ge...

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Detalles Bibliográficos
Autores principales: d’Angelo, Michele, Castelli, Vanessa, Tupone, Maria Grazia, Catanesi, Mariano, Antonosante, Andrea, Dominguez-Benot, Reyes, Ippoliti, Rodolfo, Cimini, Anna Maria, Benedetti, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862628/
https://www.ncbi.nlm.nih.gov/pubmed/31683535
http://dx.doi.org/10.3390/ijms20215422
Descripción
Sumario:Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that exert important functions in mediating the pleiotropic effects of diverse exogenous factors such as physical exercise and food components. Particularly, PPARs act as transcription factors that control the expression of genes implicated in lipid and glucose metabolism, and cellular proliferation and differentiation. In this review, we aim to summarize the recent advancements reported on the effects of lifestyle and food habits on PPAR transcriptional activity in chronic disease.

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