Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that exert important functions in mediating the pleiotropic effects of diverse exogenous factors such as physical exercise and food components. Particularly, PPARs act as transcription factors that control the expression of ge...

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Autores principales: d’Angelo, Michele, Castelli, Vanessa, Tupone, Maria Grazia, Catanesi, Mariano, Antonosante, Andrea, Dominguez-Benot, Reyes, Ippoliti, Rodolfo, Cimini, Anna Maria, Benedetti, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862628/
https://www.ncbi.nlm.nih.gov/pubmed/31683535
http://dx.doi.org/10.3390/ijms20215422
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author d’Angelo, Michele
Castelli, Vanessa
Tupone, Maria Grazia
Catanesi, Mariano
Antonosante, Andrea
Dominguez-Benot, Reyes
Ippoliti, Rodolfo
Cimini, Anna Maria
Benedetti, Elisabetta
author_facet d’Angelo, Michele
Castelli, Vanessa
Tupone, Maria Grazia
Catanesi, Mariano
Antonosante, Andrea
Dominguez-Benot, Reyes
Ippoliti, Rodolfo
Cimini, Anna Maria
Benedetti, Elisabetta
author_sort d’Angelo, Michele
collection PubMed
description Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that exert important functions in mediating the pleiotropic effects of diverse exogenous factors such as physical exercise and food components. Particularly, PPARs act as transcription factors that control the expression of genes implicated in lipid and glucose metabolism, and cellular proliferation and differentiation. In this review, we aim to summarize the recent advancements reported on the effects of lifestyle and food habits on PPAR transcriptional activity in chronic disease.
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spelling pubmed-68626282019-12-05 Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs d’Angelo, Michele Castelli, Vanessa Tupone, Maria Grazia Catanesi, Mariano Antonosante, Andrea Dominguez-Benot, Reyes Ippoliti, Rodolfo Cimini, Anna Maria Benedetti, Elisabetta Int J Mol Sci Review Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that exert important functions in mediating the pleiotropic effects of diverse exogenous factors such as physical exercise and food components. Particularly, PPARs act as transcription factors that control the expression of genes implicated in lipid and glucose metabolism, and cellular proliferation and differentiation. In this review, we aim to summarize the recent advancements reported on the effects of lifestyle and food habits on PPAR transcriptional activity in chronic disease. MDPI 2019-10-31 /pmc/articles/PMC6862628/ /pubmed/31683535 http://dx.doi.org/10.3390/ijms20215422 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
d’Angelo, Michele
Castelli, Vanessa
Tupone, Maria Grazia
Catanesi, Mariano
Antonosante, Andrea
Dominguez-Benot, Reyes
Ippoliti, Rodolfo
Cimini, Anna Maria
Benedetti, Elisabetta
Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs
title Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs
title_full Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs
title_fullStr Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs
title_full_unstemmed Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs
title_short Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs
title_sort lifestyle and food habits impact on chronic diseases: roles of ppars
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862628/
https://www.ncbi.nlm.nih.gov/pubmed/31683535
http://dx.doi.org/10.3390/ijms20215422
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