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Burden of lymphoma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016
BACKGROUND: The accurate information about lymphoma burden at national and provincial levels remains unknown in China. METHODS: Following the general analytical strategy used in GBD 2016, the age-, sex-, and province-specific incidence, mortality, and prevalence of lymphoma in China were analyzed. T...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862726/ https://www.ncbi.nlm.nih.gov/pubmed/31744509 http://dx.doi.org/10.1186/s13045-019-0785-7 |
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author | Liu, Weiping Liu, Jiangmei Song, Yuqin Zeng, Xinying Wang, Xiaopei Mi, Lan Cai, Cai Wang, Lijun Ma, Jun Zhu, Jun |
author_facet | Liu, Weiping Liu, Jiangmei Song, Yuqin Zeng, Xinying Wang, Xiaopei Mi, Lan Cai, Cai Wang, Lijun Ma, Jun Zhu, Jun |
author_sort | Liu, Weiping |
collection | PubMed |
description | BACKGROUND: The accurate information about lymphoma burden at national and provincial levels remains unknown in China. METHODS: Following the general analytical strategy used in GBD 2016, the age-, sex-, and province-specific incidence, mortality, and prevalence of lymphoma in China were analyzed. Trends in the incidence, mortality, prevalence, and disability-adjusted life years (DALYs) due to Hodgkin’s lymphoma (HL) and non-Hodgkin’s lymphoma (NHL) were assessed from 2006 to 2016. RESULTS: It was estimated that there were 75,400 new cases and 40,500 deaths of lymphoma in 2016 in China, of which 6900 new cases and 2900 deaths were due to HL, while 68,500 new cases and 37,600 deaths were due to NHL. The age-standardized incidence rate (ASIR), mortality rate (ASMR), and prevalence rate (ASPR) per 100,000 were 0.46, 0.19, and 1.75 for HL, and 4.29, 2.45, and 14.9 for NHL, respectively. An upward trend with age in incidence and mortality was observed. Males had higher incidence and mortality rates than females in all age groups. Sociodemographic index had a correlation with the ASIR (r = 0.75), ASMR (r = − 0.74), ASPR (r = 0.84), and age-standardized DALYs (r = − 0.75) of HL, as well as with the ASIR (r = 0.80), ASPR (r = 0.83), and age-standardized DALYs (r = − 0.33) of NHL. From 2006 to 2016, the age-standardized DALYs of HL decreased significantly, while the age-standardized DALYs of NHL increased from 2006 to 2013 and remained stable from 2013 to 2016. CONCLUSIONS: The burden of lymphoma in China showed unexpected patterns varied by sex, age, and provinces, with an increased trend of NHL and a decreased trend of HL from 2006 to 2016. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13045-019-0785-7) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-6862726 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-68627262019-12-11 Burden of lymphoma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016 Liu, Weiping Liu, Jiangmei Song, Yuqin Zeng, Xinying Wang, Xiaopei Mi, Lan Cai, Cai Wang, Lijun Ma, Jun Zhu, Jun J Hematol Oncol Research BACKGROUND: The accurate information about lymphoma burden at national and provincial levels remains unknown in China. METHODS: Following the general analytical strategy used in GBD 2016, the age-, sex-, and province-specific incidence, mortality, and prevalence of lymphoma in China were analyzed. Trends in the incidence, mortality, prevalence, and disability-adjusted life years (DALYs) due to Hodgkin’s lymphoma (HL) and non-Hodgkin’s lymphoma (NHL) were assessed from 2006 to 2016. RESULTS: It was estimated that there were 75,400 new cases and 40,500 deaths of lymphoma in 2016 in China, of which 6900 new cases and 2900 deaths were due to HL, while 68,500 new cases and 37,600 deaths were due to NHL. The age-standardized incidence rate (ASIR), mortality rate (ASMR), and prevalence rate (ASPR) per 100,000 were 0.46, 0.19, and 1.75 for HL, and 4.29, 2.45, and 14.9 for NHL, respectively. An upward trend with age in incidence and mortality was observed. Males had higher incidence and mortality rates than females in all age groups. Sociodemographic index had a correlation with the ASIR (r = 0.75), ASMR (r = − 0.74), ASPR (r = 0.84), and age-standardized DALYs (r = − 0.75) of HL, as well as with the ASIR (r = 0.80), ASPR (r = 0.83), and age-standardized DALYs (r = − 0.33) of NHL. From 2006 to 2016, the age-standardized DALYs of HL decreased significantly, while the age-standardized DALYs of NHL increased from 2006 to 2013 and remained stable from 2013 to 2016. CONCLUSIONS: The burden of lymphoma in China showed unexpected patterns varied by sex, age, and provinces, with an increased trend of NHL and a decreased trend of HL from 2006 to 2016. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13045-019-0785-7) contains supplementary material, which is available to authorized users. BioMed Central 2019-11-19 /pmc/articles/PMC6862726/ /pubmed/31744509 http://dx.doi.org/10.1186/s13045-019-0785-7 Text en © The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Liu, Weiping Liu, Jiangmei Song, Yuqin Zeng, Xinying Wang, Xiaopei Mi, Lan Cai, Cai Wang, Lijun Ma, Jun Zhu, Jun Burden of lymphoma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016 |
title | Burden of lymphoma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016 |
title_full | Burden of lymphoma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016 |
title_fullStr | Burden of lymphoma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016 |
title_full_unstemmed | Burden of lymphoma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016 |
title_short | Burden of lymphoma in China, 2006–2016: an analysis of the Global Burden of Disease Study 2016 |
title_sort | burden of lymphoma in china, 2006–2016: an analysis of the global burden of disease study 2016 |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862726/ https://www.ncbi.nlm.nih.gov/pubmed/31744509 http://dx.doi.org/10.1186/s13045-019-0785-7 |
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