SIRT4 silencing in tumor-associated macrophages promotes HCC development via PPARδ signalling-mediated alternative activation of macrophages

BACKGROUND: The activation of tumour-associated macrophages (TAMs) contributes to the progression of hepatocellular carcinoma (HCC). SIRT4 acts as a tumour suppressor of tumour growth by regulating cell metabolism, inflammation, and anti-tumourigenesis. However, the involvement of SIRT4 in the activ...

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Detalles Bibliográficos
Autores principales: Li, Zhi, Li, He, Zhao, Zhi-Bo, Zhu, Wei, Feng, Pan-Pan, Zhu, Xi-Wen, Gong, Jian-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862746/
https://www.ncbi.nlm.nih.gov/pubmed/31744516
http://dx.doi.org/10.1186/s13046-019-1456-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862746/
https://www.ncbi.nlm.nih.gov/pubmed/31744516
http://dx.doi.org/10.1186/s13046-019-1456-9

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