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Protective effect of Shenmai injection on doxorubicin-induced cardiotoxicity via regulation of inflammatory mediators

BACKGROUND: Doxorubicin (DOX) is a chemotherapy drug for malignant tumors. The clinical application of DOX is limited due to its dosage relative cardiotoxicity. Oxidative damage and cardiac inflammation appear to be involved in DOX-related cardiotoxicity. Shenmai injection (SMI), which mainly consis...

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Detalles Bibliográficos
Autores principales: Zhang, Sheng, You, Zhen-Qiang, Yang, Lin, Li, Li-Li, Wu, You-Ping, Gu, Li-Qiang, Xin, Yan-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862794/
https://www.ncbi.nlm.nih.gov/pubmed/31744501
http://dx.doi.org/10.1186/s12906-019-2686-2