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Exosome release and neuropathology induced by α-synuclein: new insights into protective mechanisms of Drp1 inhibition
Targeting alpha-synuclein (α-syn) as a therapeutic strategy for Parkinson’s disease (PD) has been intensively pursued largely due to its well-recognized pathogenic role. Since its discovery as the first familial link to PD over two decades ago, this protein has been associated with multiple neurotox...
Autores principales: | Fan, Rebecca Z., Guo, Min, Luo, Shouqing, Cui, Mei, Tieu, Kim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862865/ https://www.ncbi.nlm.nih.gov/pubmed/31744532 http://dx.doi.org/10.1186/s40478-019-0821-4 |
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