Cargando…

GSTA3 regulates TGF-β1-induced renal interstitial fibrosis in NRK-52E cells as a component of the PI3K–Keap1/Nrf2 pathway

OBJECTIVE: To evaluate the effect of GSTA3 within the PI3K–Keap1/Nrf2 pathway in renal interstitial fibrosis (RIF). METHODS: An in vitro RIF model with TGF-β1 stimulation in NRK-52E cells was established to identify potential signaling pathways that modulate GSTA3. Changes in GSTA3 expression were o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiao, Yun, Zhang, Zhiwei, Fu, Yingyu, Shan, Huizhi, Cui, Sini, Wu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2019
Materias:	Pre-Clinical Research Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862875/ https://www.ncbi.nlm.nih.gov/pubmed/31617428 http://dx.doi.org/10.1177/0300060519876796

Ejemplares similares

Four New Benzoylamide Derivatives Isolated from the Seeds of Lepidium apetalum Willd. and Ameliorated LPS-Induced NRK52e Cells via Nrf2/Keap1 Pathway
por: Li, Meng, et al.
Publicado: (2022)

Oleanolic acid attenuates TGF-β1-induced epithelial-mesenchymal transition in NRK-52E cells
por: He, Wei-ming, et al.
Publicado: (2018)

Role of artesunate in TGF-β1-induced renal tubular epithelial-mesenchymal transdifferentiation in NRK-52E cells
por: Zhang, Yaqian, et al.
Publicado: (2017)

GSTA3 Attenuates Renal Interstitial Fibrosis by Inhibiting TGF-Beta-Induced Tubular Epithelial-Mesenchymal Transition and Fibronectin Expression
por: Xiao, Yun, et al.
Publicado: (2016)

Suppression of CIP4/Par6 attenuates TGF-β1-induced epithelial-mesenchymal transition in NRK-52E cells
por: Zhu, Ying-Chun, et al.
Publicado: (2017)

BMP-7 Attenuates TGF-β1-Induced Fibronectin Secretion and Apoptosis of NRK-52E Cells by the Suppression of miRNA-21
por: Yu, Zhong, et al.
Publicado: (2016)

Metformin Improves Epithelial-to-Mesenchymal Transition Induced by TGF-β1 in Renal Tubular Epithelial NRK-52E Cells via Inhibiting Egr-1
por: Guan, Meiping, et al.
Publicado: (2018)

Ferulic Acid Attenuates TGF-β1-Induced Renal Cellular Fibrosis in NRK-52E Cells by Inhibiting Smad/ILK/Snail Pathway
por: Wei, Ming-gang, et al.
Publicado: (2015)

The KEAP1-NRF2 pathway: Targets for therapy and role in cancer
por: Adinolfi, Simone, et al.
Publicado: (2023)

Role of LOX-1 and ROS in oxidized low-density lipoprotein induced epithelial-mesenchymal transition of NRK52E
por: Wang, Rui, et al.
Publicado: (2010)

Flow control effect of necrostatin-1 on cell death of the NRK-52E renal tubular epithelial cell line
por: Luo, Jialun, et al.
Publicado: (2017)

A Proteomics Analysis to Evaluate Cytotoxicity in NRK-52E Cells Caused by Unmodified Nano-Fe(3)O(4)
por: Lin, Yi-Reng, et al.
Publicado: (2014)

MiR542-3p Regulates the Epithelial-Mesenchymal Transition by Directly Targeting BMP7 in NRK52e
por: Liu, Zhicheng, et al.
Publicado: (2015)

Effects of GSTA1 and GPX3 Polymorphisms on the Risk of Schizophrenia in Chinese Han Population
por: Liu, Chao, et al.
Publicado: (2020)

Galangin Suppresses Renal Inflammation via the Inhibition of NF-κB, PI3K/AKT and NLRP3 in Uric Acid Treated NRK-52E Tubular Epithelial Cells
por: Lu, Hao, et al.
Publicado: (2019)

Lefty-1 alleviates TGF-β1-induced fibroblast–myofibroblast transdifferentiation in NRK-49F cells
por: Zhang, Lijun, et al.
Publicado: (2015)

The Effect of Shen Qi Wan Medicated Serum on NRK-52E Cells Proliferation and Migration by Targeting Aquaporin 1 (AQP1)
por: He, Ying, et al.
Publicado: (2020)

The KEAP1–NRF2 System in Cancer
por: Taguchi, Keiko, et al.
Publicado: (2017)

Keap1/Nrf2 Signaling Pathway
por: Sykiotis, Gerasimos P.
Publicado: (2021)

RIDR-PI-103, ROS-activated prodrug PI3K inhibitor inhibits cell growth and impairs the PI3K/Akt pathway in BRAF and MEK inhibitor-resistant BRAF-mutant melanoma cells
por: Patel, Hima, et al.
Publicado: (2023)

The Interaction of Human Glutathione Transferase GSTA1-1 with Reactive Dyes
por: Alqarni, Mohammed Hamed, et al.
Publicado: (2021)

CircKEAP1 Suppresses the Progression of Lung Adenocarcinoma via the miR-141-3p/KEAP1/NRF2 Axis
por: Wang, Yanbo, et al.
Publicado: (2021)

Overexpression of DJ-1 reduces oxidative stress and attenuates hypoxia/reoxygenation injury in NRK-52E cells exposed to high glucose
por: Shen, Zi-Ying, et al.
Publicado: (2016)

Myoglobin Mediates Autophagy of NRK-52E in Rat Renal Tubular Epithelial Cells Via the Pink1/Parkin Signaling Pathway
por: Chen, Zhiguo, et al.
Publicado: (2020)

Structural basis of Keap1 interactions with Nrf2
por: Canning, Peter, et al.
Publicado: (2015)

Epigenetic Regulation of NRF2/KEAP1 by Phytochemicals
por: Bhattacharjee, Shamee, et al.
Publicado: (2020)

The KEAP1/NRF2 Signaling Pathway in Keratinization
por: Ishitsuka, Yosuke, et al.
Publicado: (2020)

The KEAP1-NRF2 System and Esophageal Cancer
por: Hirose, Wataru, et al.
Publicado: (2022)

Modulation of NRF2/KEAP1 Signaling in Preeclampsia
por: Tossetta, Giovanni, et al.
Publicado: (2023)

Proteomic analysis of Nrk gene-disrupted placental tissue cells explains physiological significance of NRK
por: Denda, Kimitoshi, et al.
Publicado: (2019)

Physical and Functional Interaction of Sequestosome 1 with Keap1 Regulates the Keap1-Nrf2 Cell Defense Pathway
por: Copple, Ian M., et al.
Publicado: (2010)

Reactive oxygen species induced by uric acid promote NRK-52E cell apoptosis through the NEK7-NLRP3 signaling pathway
por: Li, Dongdong, et al.
Publicado: (2021)

The analysis of GSTA1 promoter genetic and functional diversity of human populations
por: Mlakar, Vid, et al.
Publicado: (2021)

1,25-(OH)(2)D(3) ameliorates renal interstitial fibrosis in UUO rats through the AMPKα/mTOR pathway
por: Tian, Shasha, et al.
Publicado: (2021)

Impact of cytotoxic agents or apoptosis stimulants on αklotho in MDCK, NRK-52E and HK2 kidney cells
por: Münz, Sina, et al.
Publicado: (2022)

The KEAP1–NRF2 pathway regulates TFEB/TFE3-dependent lysosomal biogenesis
por: Ong, Athena Jessica S., et al.
Publicado: (2023)

Necrostatin-1 Attenuates Ischemia Injury Induced Cell Death in Rat Tubular Cell Line NRK-52E through Decreased Drp1 Expression
por: Zhang, Li, et al.
Publicado: (2013)

KEAP1 and done? Targeting the NRF2 pathway with sulforaphane
por: Dinkova-Kostova, Albena T., et al.
Publicado: (2017)

WDR23 regulates NRF2 independently of KEAP1
por: Lo, Jacqueline Y., et al.
Publicado: (2017)

Coumarins as Modulators of the Keap1/Nrf2/ARE Signaling Pathway
por: Hassanein, Emad H. M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_cec87k603v5crk38bvv3hofhum