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Advances In Research Of Spreading Through Air Spaces And The Effects On The Prognosis Of Lung Cancer

The concept of spread through air spaces (STAS) has been described as a new form of invasion in the lung in the 2015 WHO classification of Lung Tumors, namely invasion through alveolar spaces. STAS is a prognostic factor independent of growth pattern and tumor stage, and it is also an independent ris...

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Autores principales: Cao, Dandan, Sha, Jun, Cui, Rui, Han, Shuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863114/
https://www.ncbi.nlm.nih.gov/pubmed/31814767
http://dx.doi.org/10.2147/CMAR.S232187
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author Cao, Dandan
Sha, Jun
Cui, Rui
Han, Shuhua
author_facet Cao, Dandan
Sha, Jun
Cui, Rui
Han, Shuhua
author_sort Cao, Dandan
collection PubMed
description The concept of spread through air spaces (STAS) has been described as a new form of invasion in the lung in the 2015 WHO classification of Lung Tumors, namely invasion through alveolar spaces. STAS is a prognostic factor independent of growth pattern and tumor stage, and it is also an independent risk factor for unfavorable prognosis of stage I lung adenocarcinoma (ADC) and stage I lung squamous cell carcinoma (SCC). The pathological characteristics are different between ADC and SCC. STAS is not reported as routine, so setting a unified pathological reading standard, and hunting for STAS as a regular reading process is urgently advocated. We write this review to investigate the research progress of STAS and its effects on the prognosis of lung cancer.
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spelling pubmed-68631142019-12-06 Advances In Research Of Spreading Through Air Spaces And The Effects On The Prognosis Of Lung Cancer Cao, Dandan Sha, Jun Cui, Rui Han, Shuhua Cancer Manag Res Review The concept of spread through air spaces (STAS) has been described as a new form of invasion in the lung in the 2015 WHO classification of Lung Tumors, namely invasion through alveolar spaces. STAS is a prognostic factor independent of growth pattern and tumor stage, and it is also an independent risk factor for unfavorable prognosis of stage I lung adenocarcinoma (ADC) and stage I lung squamous cell carcinoma (SCC). The pathological characteristics are different between ADC and SCC. STAS is not reported as routine, so setting a unified pathological reading standard, and hunting for STAS as a regular reading process is urgently advocated. We write this review to investigate the research progress of STAS and its effects on the prognosis of lung cancer. Dove 2019-11-15 /pmc/articles/PMC6863114/ /pubmed/31814767 http://dx.doi.org/10.2147/CMAR.S232187 Text en © 2019 Cao et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Cao, Dandan
Sha, Jun
Cui, Rui
Han, Shuhua
Advances In Research Of Spreading Through Air Spaces And The Effects On The Prognosis Of Lung Cancer
title Advances In Research Of Spreading Through Air Spaces And The Effects On The Prognosis Of Lung Cancer
title_full Advances In Research Of Spreading Through Air Spaces And The Effects On The Prognosis Of Lung Cancer
title_fullStr Advances In Research Of Spreading Through Air Spaces And The Effects On The Prognosis Of Lung Cancer
title_full_unstemmed Advances In Research Of Spreading Through Air Spaces And The Effects On The Prognosis Of Lung Cancer
title_short Advances In Research Of Spreading Through Air Spaces And The Effects On The Prognosis Of Lung Cancer
title_sort advances in research of spreading through air spaces and the effects on the prognosis of lung cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863114/
https://www.ncbi.nlm.nih.gov/pubmed/31814767
http://dx.doi.org/10.2147/CMAR.S232187
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