Cargando…

Cryptosporidiosis And Other Intestinal Parasitic Infections And Concomitant Threats Among HIV-Infected Children In Southern Ethiopia Receiving First-Line Antiretroviral Therapy

BACKGROUND: Children infected with human immunodeficiency virus (HIV) are at high risk of acquiring intestinal parasitic infections. This study aimed to determine the magnitude of Cryptosporidium and other intestinal parasitic infections and concomitant threats among HIV-infected children. METHODS:...

Descripción completa

Detalles Bibliográficos
Autores principales: Gebre, Blatu, Alemayehu, Tsegaye, Girma, Mekonin, Ayalew, Freshwork, Tadesse, Birkneh Tilahun, Shemelis, Techalew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863180/
https://www.ncbi.nlm.nih.gov/pubmed/31814775
http://dx.doi.org/10.2147/HIV.S215417
_version_ 1783471701329182720
author Gebre, Blatu
Alemayehu, Tsegaye
Girma, Mekonin
Ayalew, Freshwork
Tadesse, Birkneh Tilahun
Shemelis, Techalew
author_facet Gebre, Blatu
Alemayehu, Tsegaye
Girma, Mekonin
Ayalew, Freshwork
Tadesse, Birkneh Tilahun
Shemelis, Techalew
author_sort Gebre, Blatu
collection PubMed
description BACKGROUND: Children infected with human immunodeficiency virus (HIV) are at high risk of acquiring intestinal parasitic infections. This study aimed to determine the magnitude of Cryptosporidium and other intestinal parasitic infections and concomitant threats among HIV-infected children. METHODS: A hospital-based cross-sectional study was carried out at three antiretroviral therapy clinics in southern Ethiopia from February 2016 to June 2017 in 384 HIV positive children. Socio-demographic and clinical data were collected using structured questionnaires. Direct stool microscopic examination and modified Zeihl–Neelsen staining technique to identify parasites. Chi-square test was conducted to determine the real predictors of the infection. Significant association was considered when p-value <0.05 at 95% CI. RESULTS: The overall magnitude of intestinal parasitic infections among the study population was 16.9% (95% CI: 13.0–20.8%). The most predominant parasitic infections were Cryptosporidium spp. (9.6%) and the least was Taenia spp. (0.78%). Diarrheal status (χ(2)=7.653, df=2, p=0.022) was detected to be the only significant associated variable. CONCLUSION: Cryptosporidium infection was found to be the most common intestinal parasitosis among HIV-infected children. Routine screening service for Cryptosporidium and other intestinal parasites is important in the clinical management of HIV-infected children.
format Online
Article
Text
id pubmed-6863180
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Dove
record_format MEDLINE/PubMed
spelling pubmed-68631802019-12-06 Cryptosporidiosis And Other Intestinal Parasitic Infections And Concomitant Threats Among HIV-Infected Children In Southern Ethiopia Receiving First-Line Antiretroviral Therapy Gebre, Blatu Alemayehu, Tsegaye Girma, Mekonin Ayalew, Freshwork Tadesse, Birkneh Tilahun Shemelis, Techalew HIV AIDS (Auckl) Original Research BACKGROUND: Children infected with human immunodeficiency virus (HIV) are at high risk of acquiring intestinal parasitic infections. This study aimed to determine the magnitude of Cryptosporidium and other intestinal parasitic infections and concomitant threats among HIV-infected children. METHODS: A hospital-based cross-sectional study was carried out at three antiretroviral therapy clinics in southern Ethiopia from February 2016 to June 2017 in 384 HIV positive children. Socio-demographic and clinical data were collected using structured questionnaires. Direct stool microscopic examination and modified Zeihl–Neelsen staining technique to identify parasites. Chi-square test was conducted to determine the real predictors of the infection. Significant association was considered when p-value <0.05 at 95% CI. RESULTS: The overall magnitude of intestinal parasitic infections among the study population was 16.9% (95% CI: 13.0–20.8%). The most predominant parasitic infections were Cryptosporidium spp. (9.6%) and the least was Taenia spp. (0.78%). Diarrheal status (χ(2)=7.653, df=2, p=0.022) was detected to be the only significant associated variable. CONCLUSION: Cryptosporidium infection was found to be the most common intestinal parasitosis among HIV-infected children. Routine screening service for Cryptosporidium and other intestinal parasites is important in the clinical management of HIV-infected children. Dove 2019-11-15 /pmc/articles/PMC6863180/ /pubmed/31814775 http://dx.doi.org/10.2147/HIV.S215417 Text en © 2019 Gebre et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Gebre, Blatu
Alemayehu, Tsegaye
Girma, Mekonin
Ayalew, Freshwork
Tadesse, Birkneh Tilahun
Shemelis, Techalew
Cryptosporidiosis And Other Intestinal Parasitic Infections And Concomitant Threats Among HIV-Infected Children In Southern Ethiopia Receiving First-Line Antiretroviral Therapy
title Cryptosporidiosis And Other Intestinal Parasitic Infections And Concomitant Threats Among HIV-Infected Children In Southern Ethiopia Receiving First-Line Antiretroviral Therapy
title_full Cryptosporidiosis And Other Intestinal Parasitic Infections And Concomitant Threats Among HIV-Infected Children In Southern Ethiopia Receiving First-Line Antiretroviral Therapy
title_fullStr Cryptosporidiosis And Other Intestinal Parasitic Infections And Concomitant Threats Among HIV-Infected Children In Southern Ethiopia Receiving First-Line Antiretroviral Therapy
title_full_unstemmed Cryptosporidiosis And Other Intestinal Parasitic Infections And Concomitant Threats Among HIV-Infected Children In Southern Ethiopia Receiving First-Line Antiretroviral Therapy
title_short Cryptosporidiosis And Other Intestinal Parasitic Infections And Concomitant Threats Among HIV-Infected Children In Southern Ethiopia Receiving First-Line Antiretroviral Therapy
title_sort cryptosporidiosis and other intestinal parasitic infections and concomitant threats among hiv-infected children in southern ethiopia receiving first-line antiretroviral therapy
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863180/
https://www.ncbi.nlm.nih.gov/pubmed/31814775
http://dx.doi.org/10.2147/HIV.S215417
work_keys_str_mv AT gebreblatu cryptosporidiosisandotherintestinalparasiticinfectionsandconcomitantthreatsamonghivinfectedchildreninsouthernethiopiareceivingfirstlineantiretroviraltherapy
AT alemayehutsegaye cryptosporidiosisandotherintestinalparasiticinfectionsandconcomitantthreatsamonghivinfectedchildreninsouthernethiopiareceivingfirstlineantiretroviraltherapy
AT girmamekonin cryptosporidiosisandotherintestinalparasiticinfectionsandconcomitantthreatsamonghivinfectedchildreninsouthernethiopiareceivingfirstlineantiretroviraltherapy
AT ayalewfreshwork cryptosporidiosisandotherintestinalparasiticinfectionsandconcomitantthreatsamonghivinfectedchildreninsouthernethiopiareceivingfirstlineantiretroviraltherapy
AT tadessebirknehtilahun cryptosporidiosisandotherintestinalparasiticinfectionsandconcomitantthreatsamonghivinfectedchildreninsouthernethiopiareceivingfirstlineantiretroviraltherapy
AT shemelistechalew cryptosporidiosisandotherintestinalparasiticinfectionsandconcomitantthreatsamonghivinfectedchildreninsouthernethiopiareceivingfirstlineantiretroviraltherapy