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Stabilization and formulation of a recombinant Human Cytomegalovirus vector for use as a candidate HIV-1 vaccine
Live attenuated viral vaccine/vector candidates are inherently unstable and infectivity titer losses can readily occur without defining appropriate formulations, storage conditions and clinical handling practices. During initial process development of a candidate vaccine against HIV-1 using a recomb...
Autores principales: | Kumru, Ozan S., Saleh-Birdjandi, Soraia, Antunez, Lorena R., Sayeed, Eddy, Robinson, David, van den Worm, Sjoerd, Diemer, Geoffrey S., Perez, Wilma, Caposio, Patrizia, Früh, Klaus, Joshi, Sangeeta B., Volkin, David B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863464/ https://www.ncbi.nlm.nih.gov/pubmed/31548012 http://dx.doi.org/10.1016/j.vaccine.2019.09.027 |
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