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Aging boosts antiviral CD8(+)T cell memory through improved engagement of diversified recall response determinants
The determinants of protective CD8(+) memory T cell (CD8(+)T(M)) immunity remain incompletely defined and may in fact constitute an evolving agency as aging CD8(+)T(M) progressively acquire enhanced rather than impaired recall capacities. Here, we show that old as compared to young antiviral CD8(+)T...
Autores principales: | Davenport, Bennett, Eberlein, Jens, Nguyen, Tom T., Victorino, Francisco, Jhun, Kevin, Abuirqeba, Haedar, van der Heide, Verena, Heeger, Peter, Homann, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863560/ https://www.ncbi.nlm.nih.gov/pubmed/31697793 http://dx.doi.org/10.1371/journal.ppat.1008144 |
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