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Comparison of backbone dynamics of the p50 dimerization domain of NFκB in the homodimeric transcription factor NFκB1 and in its heterodimeric complex with RelA (p65)

The nuclear factor of kappa light polypeptide gene enhancer in B‐cells (NFκB) transcription factors play a critical role in human immune response. The family includes homodimers and heterodimers of five component proteins, which mediate different transcriptional responses and bind preferentially to...

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Detalles Bibliográficos
Autores principales: Kohl, Bastian, Granitzka, Vanessa, Singh, Amrinder, Quintas, Pedro, Xiromeriti, Elli, Mörtel, Fabian, Wright, Peter E., Kroon, Gerard, Dyson, H. Jane, Stoll, Raphael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863704/
https://www.ncbi.nlm.nih.gov/pubmed/31587407
http://dx.doi.org/10.1002/pro.3736