Cargando…

Eukaryotic elongation factor 2 kinase inhibitor, A484954 potentiates β-adrenergic receptor agonist-induced acute decrease in diastolic blood pressure in rats

Eukaryotic elongation factor 2 (eEF2) kinase (eEF2K) acts to inhibit protein translation through phosphorylating a specific substrate, eEF2. We previously found that the increased eEF2K expression in mesenteric artery mediates hypertension development in spontaneously hypertensive rats. More recentl...

Descripción completa

Detalles Bibliográficos
Autores principales:	KODAMA, Tomoko, OKADA, Muneyoshi, YAMAWAKI, Hideyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Japanese Society of Veterinary Science 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863711/ https://www.ncbi.nlm.nih.gov/pubmed/31484844 http://dx.doi.org/10.1292/jvms.19-0425

Ejemplares similares

Eukaryotic elongation factor 2 kinase inhibitor, A484954 inhibits noradrenaline-induced acute increase of blood pressure in rats
por: KODAMA, Tomoko, et al.
Publicado: (2018)

Age-dependent increase in activity of eukaryotic elongation factor 2 kinase in mesenteric arteries from spontaneously hypertensive rats
por: KODAMA, Tomoko, et al.
Publicado: (2020)

Chemerin fragments show different effects on systemic blood pressure dependent on carboxyl-terminal cleavage site
por: YAMAMOTO, Atsunori, et al.
Publicado: (2022)

Autocrine role of senescent cardiac fibroblasts-derived extracellular vesicles
por: FUJIOKA, Yusei, et al.
Publicado: (2023)

Coordination of changes in expression and phosphorylation of eukaryotic elongation factor 2 (eEF2) and eEF2 kinase in hypertrophied cardiomyocytes
por: Kameshima, Satoshi, et al.
Publicado: (2016)

Diverse distribution of tyrosine receptor kinase B isoforms in rat multiple tissues
por: OTANI, Kosuke, et al.
Publicado: (2017)

Mechanisms Underlying a Decrease in KCl-Induced Contraction after Long-Term Serum-Free Organ Culture of Rat Isolated Mesenteric Artery
por: MORITA, Tomoka, et al.
Publicado: (2014)

A single injection of periostin decreases cardiac voltage-gated Na(+) channel in rat ventricles
por: IMOTO, Keisuke, et al.
Publicado: (2021)

Endostatin inhibits T-type Ca(2+) channel current in guinea pig ventricular myocyte
por: YASUDA, Jumpei, et al.
Publicado: (2015)

Expression profile of matricellular proteins in hypertrophied right ventricle of monocrotaline-induced pulmonary hypertensive rats
por: IMOTO, Keisuke, et al.
Publicado: (2017)

Cathepsin S degrades arresten and canstatin in infarcted area after myocardial infarction in rats
por: SUGIYAMA, Akira, et al.
Publicado: (2019)

Plasma small extracellular vesicles in hypertensive rats impair reactivity of isolated blood vessels
por: FUJIOKA, Yusei, et al.
Publicado: (2020)

Thrombospondin-4 induces prolongation of action potential duration in rat isolated ventricular myocytes
por: IMOTO, Keisuke, et al.
Publicado: (2020)

Small extracellular vesicles from rat plasma promote migration and proliferation of vascular smooth muscle cells
por: OTANI, Kosuke, et al.
Publicado: (2020)

Human Omentin-1 Administration Ameliorates Hypertensive Complications without Affecting Hypertension in Spontaneously Hypertensive Rats
por: Okamura, Yuta, et al.
Publicado: (2023)

Canstatin inhibits hypoxia-induced apoptosis through activation of integrin/focal adhesion kinase/Akt signaling pathway in H9c2 cardiomyoblasts
por: Kanazawa, Hiroki, et al.
Publicado: (2017)

Decreased Expression of Canstatin in Rat Model of Monocrotaline-Induced Pulmonary Arterial Hypertension: Protective Effect of Canstatin on Right Ventricular Remodeling
por: Sugiyama, Akira, et al.
Publicado: (2020)

Impairing Eukaryotic Elongation Factor 2 Kinase Activity Decreases Atherosclerotic Plaque Formation
por: Zhang, Peng, et al.
Publicado: (2014)

Cardioprotective Effect of Ulmus wallichiana Planchon in β-Adrenergic Agonist Induced Cardiac Hypertrophy
por: Syed, Anees A., et al.
Publicado: (2016)

Alpha-Adrenergic Agonists Stimulate Fluid Secretion in Lacrimal Gland Ducts
por: Szarka, Dóra, et al.
Publicado: (2020)

Periostin Mediates Right Ventricular Failure through Induction of Inducible Nitric Oxide Synthase Expression in Right Ventricular Fibroblasts from Monocrotaline-Induced Pulmonary Arterial Hypertensive Rats
por: Imoto, Keisuke, et al.
Publicado: (2018)

Sinigrin Enhanced Antiasthmatic Effects of Beta Adrenergic Receptors Agonists by Regulating cAMP-Mediated Pathways
por: Chu, Simeng, et al.
Publicado: (2020)

Salmeterol, a β2 Adrenergic Agonist, Promotes Adult Hippocampal Neurogenesis in a Region-Specific Manner
por: Bortolotto, Valeria, et al.
Publicado: (2019)

Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase
por: Pyr Dit Ruys, Sébastien, et al.
Publicado: (2012)

Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase
por: Ruys, S. Pyr Dit, et al.
Publicado: (2012)

Endostatin inhibits bradykinin-induced cardiac contraction
por: YASUDA, Jumpei, et al.
Publicado: (2015)

Endostatin Stimulates Proliferation and Migration of Myofibroblasts Isolated from Myocardial Infarction Model Rats
por: Sugiyama, Akira, et al.
Publicado: (2018)

Long-term administration of recombinant canstatin prevents adverse cardiac remodeling after myocardial infarction
por: Sugiyama, Akira, et al.
Publicado: (2020)

Optimal Isolation Method of Small Extracellular Vesicles from Rat Plasma
por: Otani, Kosuke, et al.
Publicado: (2019)

Chemokine-like Receptor 1 in Brain of Spontaneously Hypertensive Rats Mediates Systemic Hypertension
por: Yamamoto, Atsunori, et al.
Publicado: (2021)

Insights Into the Pathologic Roles and Regulation of Eukaryotic Elongation Factor-2 Kinase
por: Ballard, Darby J., et al.
Publicado: (2021)

Beta-Adrenergic Agonists
por: Barisione, Giovanni, et al.
Publicado: (2010)

Long-Acting β(2) Adrenergic Receptor Agonist Ameliorates Imiquimod-Induced Psoriasis-Like Skin Lesion by Regulating Keratinocyte Proliferation and Apoptosis
por: Xu, Rui, et al.
Publicado: (2022)

Control of eukaryotic transcription elongation
por: Winston, Fred
Publicado: (2001)

Cardiovascular Characteristics of Zucker Fatty Diabetes Mellitus Rats, an Animal Model for Obesity and Type 2 Diabetes
por: Otani, Kosuke, et al.
Publicado: (2022)

Preventive Effect of Canstatin against Ventricular Arrhythmia Induced by Ischemia/Reperfusion Injury: A Pilot Study
por: Sugiyama, Akira, et al.
Publicado: (2021)

Eukaryotic Elongation Factor 2 Kinase (eEF2K) in Cancer
por: Wang, Xuemin, et al.
Publicado: (2017)

Structural basis for the calmodulin-mediated activation of eukaryotic elongation factor 2 kinase
por: Piserchio, Andrea, et al.
Publicado: (2022)

ADP enhances the allosteric activation of eukaryotic elongation factor 2 kinase by calmodulin
por: Piserchio, Andrea, et al.
Publicado: (2023)

Beta-Adrenergic Blockade in Critical Illness
por: Bruning, Rebecca, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0v1ff3stl5v2jj0um9irptqtbr