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Binding of FAD and tryptophan to the tryptophan 6‐halogenase Thal is negatively coupled
Flavin‐dependent halogenases require reduced flavin adenine dinucleotide (FADH(2)), O(2), and halide salts to halogenate their substrates. We describe the crystal structures of the tryptophan 6‐halogenase Thal in complex with FAD or with both tryptophan and FAD. If tryptophan and FAD were soaked sim...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863734/ https://www.ncbi.nlm.nih.gov/pubmed/31589794 http://dx.doi.org/10.1002/pro.3739 |