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Potential Inhibitors of Galactofuranosyltransferase 2 (GlfT2): Molecular Docking, 3D-QSAR, and In Silico ADMETox Studies

A strategy in the discovery of anti-tuberculosis (anti-TB) drug involves targeting the enzymes involved in the biosynthesis of Mycobacterium tuberculosis’ (Mtb) cell wall. One of these enzymes is Galactofuranosyltransferase 2 (GlfT2) that catalyzes the elongation of the galactan chain of Mtb cell wa...

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Detalles Bibliográficos
Autores principales:	Ortiz, Christopher Llynard D., Completo, Gladys C., Nacario, Ruel C., Nellas, Ricky B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863818/ https://www.ncbi.nlm.nih.gov/pubmed/31745103 http://dx.doi.org/10.1038/s41598-019-52764-8

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