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A simple, high-throughput stabilization assay to test HIV-1 uncoating inhibitors

Shortly after entering the cell, HIV-1 copies its genomic RNA into double-stranded DNA in a process known as reverse transcription. This process starts inside a core consisting of an enclosed lattice of capsid proteins that protect the viral RNA from cytosolic sensors and degradation pathways. To ac...

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Detalles Bibliográficos
Autores principales:	Dostálková, Alžběta, Hadravová, Romana, Kaufman, Filip, Křížová, Ivana, Škach, Kryštof, Flegel, Martin, Hrabal, Richard, Ruml, Tomáš, Rumlová, Michaela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863892/ https://www.ncbi.nlm.nih.gov/pubmed/31745222 http://dx.doi.org/10.1038/s41598-019-53483-w

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