Fanconi anemia proteins counteract the implementation of the oncogene-induced senescence program

Fanconi Anemia (FA), due to the loss-of-function of the proteins that constitute the FANC pathway involved in DNA replication and genetic stability maintainance, is a rare genetic disease featuring bone marrow failure, developmental abnormalities and cancer predisposition. Similar clinical stigmas h...

Descripción completa

Detalles Bibliográficos
Autores principales: Helbling-Leclerc, Anne, Dessarps-Freichey, Françoise, Evrard, Caroline, Rosselli, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863893/
https://www.ncbi.nlm.nih.gov/pubmed/31745226
http://dx.doi.org/10.1038/s41598-019-53502-w

Ejemplares similares

Ejemplares similares