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Feedforward discharges couple the singing central pattern generator and ventilation central pattern generator in the cricket abdominal central nervous system

We investigated the central nervous coordination between singing motor activity and abdominal ventilatory pumping in crickets. Fictive singing, with sensory feedback removed, was elicited by eserine-microinjection into the brain, and the motor activity underlying singing and abdominal ventilation wa...

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Autores principales: Schöneich, Stefan, Hedwig, Berthold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863954/
https://www.ncbi.nlm.nih.gov/pubmed/31691096
http://dx.doi.org/10.1007/s00359-019-01377-7
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author Schöneich, Stefan
Hedwig, Berthold
author_facet Schöneich, Stefan
Hedwig, Berthold
author_sort Schöneich, Stefan
collection PubMed
description We investigated the central nervous coordination between singing motor activity and abdominal ventilatory pumping in crickets. Fictive singing, with sensory feedback removed, was elicited by eserine-microinjection into the brain, and the motor activity underlying singing and abdominal ventilation was recorded with extracellular electrodes. During singing, expiratory abdominal muscle activity is tightly phase coupled to the chirping pattern. Occasional temporary desynchronization of the two motor patterns indicate discrete central pattern generator (CPG) networks that can operate independently. Intracellular recordings revealed a sub-threshold depolarization in phase with the ventilatory cycle in a singing-CPG interneuron, and in a ventilation-CPG interneuron an excitatory input in phase with each syllable of the chirps. Inhibitory synaptic inputs coupled to the syllables of the singing motor pattern were present in another ventilatory interneuron, which is not part of the ventilation-CPG. Our recordings suggest that the two centrally generated motor patterns are coordinated by reciprocal feedforward discharges from the singing-CPG to the ventilation-CPG and vice versa. Consequently, expiratory contraction of the abdomen usually occurs in phase with the chirps and ventilation accelerates during singing due to entrainment by the faster chirp cycle.
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spelling pubmed-68639542019-12-05 Feedforward discharges couple the singing central pattern generator and ventilation central pattern generator in the cricket abdominal central nervous system Schöneich, Stefan Hedwig, Berthold J Comp Physiol A Neuroethol Sens Neural Behav Physiol Original Paper We investigated the central nervous coordination between singing motor activity and abdominal ventilatory pumping in crickets. Fictive singing, with sensory feedback removed, was elicited by eserine-microinjection into the brain, and the motor activity underlying singing and abdominal ventilation was recorded with extracellular electrodes. During singing, expiratory abdominal muscle activity is tightly phase coupled to the chirping pattern. Occasional temporary desynchronization of the two motor patterns indicate discrete central pattern generator (CPG) networks that can operate independently. Intracellular recordings revealed a sub-threshold depolarization in phase with the ventilatory cycle in a singing-CPG interneuron, and in a ventilation-CPG interneuron an excitatory input in phase with each syllable of the chirps. Inhibitory synaptic inputs coupled to the syllables of the singing motor pattern were present in another ventilatory interneuron, which is not part of the ventilation-CPG. Our recordings suggest that the two centrally generated motor patterns are coordinated by reciprocal feedforward discharges from the singing-CPG to the ventilation-CPG and vice versa. Consequently, expiratory contraction of the abdomen usually occurs in phase with the chirps and ventilation accelerates during singing due to entrainment by the faster chirp cycle. Springer Berlin Heidelberg 2019-11-05 2019 /pmc/articles/PMC6863954/ /pubmed/31691096 http://dx.doi.org/10.1007/s00359-019-01377-7 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Paper
Schöneich, Stefan
Hedwig, Berthold
Feedforward discharges couple the singing central pattern generator and ventilation central pattern generator in the cricket abdominal central nervous system
title Feedforward discharges couple the singing central pattern generator and ventilation central pattern generator in the cricket abdominal central nervous system
title_full Feedforward discharges couple the singing central pattern generator and ventilation central pattern generator in the cricket abdominal central nervous system
title_fullStr Feedforward discharges couple the singing central pattern generator and ventilation central pattern generator in the cricket abdominal central nervous system
title_full_unstemmed Feedforward discharges couple the singing central pattern generator and ventilation central pattern generator in the cricket abdominal central nervous system
title_short Feedforward discharges couple the singing central pattern generator and ventilation central pattern generator in the cricket abdominal central nervous system
title_sort feedforward discharges couple the singing central pattern generator and ventilation central pattern generator in the cricket abdominal central nervous system
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863954/
https://www.ncbi.nlm.nih.gov/pubmed/31691096
http://dx.doi.org/10.1007/s00359-019-01377-7
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