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A Novel Fully-Human Potency-Matched Dual Cytokine-Antibody Fusion Protein Targets Carbonic Anhydrase IX in Renal Cell Carcinomas

Certain cytokines synergize in activating anti-cancer immunity at the site of disease and it may be desirable to generate biopharmaceutical agents, capable of simultaneous delivery of cytokine pairs to the tumor. In this article, we have described the cloning, expression and characterization of IL2-...

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Detalles Bibliográficos
Autores principales:	De Luca, Roberto, Gouyou, Baptiste, Ongaro, Tiziano, Villa, Alessandra, Ziffels, Barbara, Sannino, Alessandro, Buttinoni, Gianluca, Galeazzi, Simone, Mazzacuva, Mirko, Neri, Dario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863974/ https://www.ncbi.nlm.nih.gov/pubmed/31799191 http://dx.doi.org/10.3389/fonc.2019.01228

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