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Statistical multiscale mapping of IDH1, MGMT, and microvascular proliferation in human brain tumors from multiparametric MR and spatially-registered core biopsy

We propose a statistical multiscale mapping approach to identify microscopic and molecular heterogeneity across a tumor microenvironment using multiparametric MR (mp-MR). Twenty-nine patients underwent pre-surgical mp-MR followed by MR-guided stereotactic core biopsy. The locations of the biopsy cor...

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Detalles Bibliográficos
Autores principales:	Parker, Jason G., Diller, Emily E., Cao, Sha, Nelson, Jeremy T., Yeom, Kristen, Ho, Chang, Lober, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864039/ https://www.ncbi.nlm.nih.gov/pubmed/31745125 http://dx.doi.org/10.1038/s41598-019-53256-5

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