Exploring anticancer activity of structurally modified benzylphenoxyacetamide (BPA); I: Synthesis strategies and computational analyses of substituted BPA variants with high anti-glioblastoma potential

Structural variations of the benzylphenoxyacetamide (BPA) molecular skeleton were explored as a viable starting point for designing new anti-glioblastoma drug candidates. Hand-to-hand computational evaluation, chemical modifications, and cell viability testing were performed to explore the importanc...

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Detalles Bibliográficos
Autores principales: Stalinska, Joanna, Houser, Lisa, Rak, Monika, Colley, Susan B., Reiss, Krzysztof, Jursic, Branko S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864087/
https://www.ncbi.nlm.nih.gov/pubmed/31745126
http://dx.doi.org/10.1038/s41598-019-53207-0

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