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The tumor vasculature an attractive CAR T cell target in solid tumors
T cells armed with a chimeric antigen receptor, CAR T cells, have shown extraordinary activity against certain B lymphocyte malignancies, when targeted towards the CD19 B cell surface marker. These results have led to the regulatory approval of two CAR T cell approaches. Translation of this result t...
Autores principales: | Akbari, Parvin, Huijbers, Elisabeth J. M., Themeli, Maria, Griffioen, Arjan W., van Beijnum, Judy R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864117/ https://www.ncbi.nlm.nih.gov/pubmed/31628559 http://dx.doi.org/10.1007/s10456-019-09687-9 |
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