De-Novo-Designed Translation-Repressing Riboregulators for Multi-Input Cellular Logic

Efforts to construct synthetic biological circuits with more complex functions have often been hindered by the idiosyncratic behavior, limited dynamic range, and crosstalk of commonly utilized parts. Here, we employ de novo RNA design to develop two high-performance translational repressors with sen...

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Detalles Bibliográficos
Autores principales: Kim, Jongmin, Zhou, Yu, Carlson, Paul D., Teichmann, Mario, Chaudhary, Soma, Simmel, Friedrich C., Silver, Pamela A., Collins, James J., Lucks, Julius B., Yin, Peng, Green, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864284/
https://www.ncbi.nlm.nih.gov/pubmed/31686032
http://dx.doi.org/10.1038/s41589-019-0388-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864284/
https://www.ncbi.nlm.nih.gov/pubmed/31686032
http://dx.doi.org/10.1038/s41589-019-0388-1

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