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De-Novo-Designed Translation-Repressing Riboregulators for Multi-Input Cellular Logic
Efforts to construct synthetic biological circuits with more complex functions have often been hindered by the idiosyncratic behavior, limited dynamic range, and crosstalk of commonly utilized parts. Here, we employ de novo RNA design to develop two high-performance translational repressors with sen...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864284/ https://www.ncbi.nlm.nih.gov/pubmed/31686032 http://dx.doi.org/10.1038/s41589-019-0388-1 |