Single-Cell RNA-seq Reveals Profound Alterations in Mechanosensitive Dorsal Root Ganglion Neurons with Vitamin E Deficiency

Ninety percent of Americans consume less than the estimated average requirements of dietary vitamin E (vitE). Severe vitE deficiency due to genetic mutations in the tocopherol transfer protein (TTPA) in humans results in ataxia with vitE deficiency (AVED), with proprioceptive deficits and somatosens...

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Detalles Bibliográficos
Autores principales: Finno, Carrie J., Peterson, Janel, Kang, Mincheol, Park, Seojin, Bordbari, Matthew H., Durbin-Johnson, Blythe, Settles, Matthew, Perez-Flores, Maria C., Lee, Jeong H., Yamoah, Ebenezer N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864320/
https://www.ncbi.nlm.nih.gov/pubmed/31733517
http://dx.doi.org/10.1016/j.isci.2019.10.064

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