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A case of thymoma in myasthenia gravis: Successful outcome after thymectomy()

INTRODUCTION: Thymic abnormalities occur as hyperplasia and thymoma. Myasthenia gravis is commonly present in thymoma. Thymectomy possesses risk due to anatomical proximity with vital thoracic structures and myasthenia crisis. PRESENTATION OF CASE: Forty five years female with complaints of difficul...

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Autores principales: Dahal, S., Bhandari, N., Dhakal, P., Karmacharya, R.M., Singh, A.K., Tuladhar, S.M., Devbhandari, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864328/
https://www.ncbi.nlm.nih.gov/pubmed/31734473
http://dx.doi.org/10.1016/j.ijscr.2019.10.069
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author Dahal, S.
Bhandari, N.
Dhakal, P.
Karmacharya, R.M.
Singh, A.K.
Tuladhar, S.M.
Devbhandari, M.
author_facet Dahal, S.
Bhandari, N.
Dhakal, P.
Karmacharya, R.M.
Singh, A.K.
Tuladhar, S.M.
Devbhandari, M.
author_sort Dahal, S.
collection PubMed
description INTRODUCTION: Thymic abnormalities occur as hyperplasia and thymoma. Myasthenia gravis is commonly present in thymoma. Thymectomy possesses risk due to anatomical proximity with vital thoracic structures and myasthenia crisis. PRESENTATION OF CASE: Forty five years female with complaints of difficulty swallowing and weakness of upper limb muscles upon investigation showed mass in mediastinum and antibody test for myasthenia gravis positive. Medical management was done for a month followed by thymectomy. There were no intra and postoperative complications. Medical management was stopped one month after surgery and she is symptom free. DISCUSSION: Thymectomy is the standard of care where median sternotomy is the mainstay approach to surgery. Various other surgical approaches and complications revolving around surgery has been discussed. CONCLUSION: Surgical removal of thymoma cured myasthenia gravis in our case. We focused on proper preoperative optimization of myasthenia gravis symptoms before thymectomy.
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spelling pubmed-68643282019-11-22 A case of thymoma in myasthenia gravis: Successful outcome after thymectomy() Dahal, S. Bhandari, N. Dhakal, P. Karmacharya, R.M. Singh, A.K. Tuladhar, S.M. Devbhandari, M. Int J Surg Case Rep Article INTRODUCTION: Thymic abnormalities occur as hyperplasia and thymoma. Myasthenia gravis is commonly present in thymoma. Thymectomy possesses risk due to anatomical proximity with vital thoracic structures and myasthenia crisis. PRESENTATION OF CASE: Forty five years female with complaints of difficulty swallowing and weakness of upper limb muscles upon investigation showed mass in mediastinum and antibody test for myasthenia gravis positive. Medical management was done for a month followed by thymectomy. There were no intra and postoperative complications. Medical management was stopped one month after surgery and she is symptom free. DISCUSSION: Thymectomy is the standard of care where median sternotomy is the mainstay approach to surgery. Various other surgical approaches and complications revolving around surgery has been discussed. CONCLUSION: Surgical removal of thymoma cured myasthenia gravis in our case. We focused on proper preoperative optimization of myasthenia gravis symptoms before thymectomy. Elsevier 2019-11-05 /pmc/articles/PMC6864328/ /pubmed/31734473 http://dx.doi.org/10.1016/j.ijscr.2019.10.069 Text en © 2019 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dahal, S.
Bhandari, N.
Dhakal, P.
Karmacharya, R.M.
Singh, A.K.
Tuladhar, S.M.
Devbhandari, M.
A case of thymoma in myasthenia gravis: Successful outcome after thymectomy()
title A case of thymoma in myasthenia gravis: Successful outcome after thymectomy()
title_full A case of thymoma in myasthenia gravis: Successful outcome after thymectomy()
title_fullStr A case of thymoma in myasthenia gravis: Successful outcome after thymectomy()
title_full_unstemmed A case of thymoma in myasthenia gravis: Successful outcome after thymectomy()
title_short A case of thymoma in myasthenia gravis: Successful outcome after thymectomy()
title_sort case of thymoma in myasthenia gravis: successful outcome after thymectomy()
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864328/
https://www.ncbi.nlm.nih.gov/pubmed/31734473
http://dx.doi.org/10.1016/j.ijscr.2019.10.069
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