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A Report on Fungal (1→3)-α-d-glucans: Properties, Functions and Application

The cell walls of fungi are composed of glycoproteins, chitin, and α- and β-glucans. Although there are many reports on β-glucans, α-glucan polysaccharides are not yet fully understood. This review characterizes the physicochemical properties and functions of (1→3)-α-d-glucans. Particular attention...

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Detalles Bibliográficos
Autores principales: Złotko, Katarzyna, Wiater, Adrian, Waśko, Adam, Pleszczyńska, Małgorzata, Paduch, Roman, Jaroszuk-Ściseł, Jolanta, Bieganowski, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864487/
https://www.ncbi.nlm.nih.gov/pubmed/31684030
http://dx.doi.org/10.3390/molecules24213972
Descripción
Sumario:The cell walls of fungi are composed of glycoproteins, chitin, and α- and β-glucans. Although there are many reports on β-glucans, α-glucan polysaccharides are not yet fully understood. This review characterizes the physicochemical properties and functions of (1→3)-α-d-glucans. Particular attention has been paid to practical application and the effect of glucans in various respects, taking into account unfavourable effects and potential use. The role of α-glucans in plant infection has been proven, and collected facts have confirmed the characteristics of Aspergillus fumigatus infection associated with the presence of glucan in fungal cell wall. Like β-glucans, there are now evidence that α-glucans can also stimulate the immune system. Moreover, α-d-glucans have the ability to induce mutanases and can thus decompose plaque.