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Engineered Cardiac Pacemaker Nodes Created by TBX18 Gene Transfer Overcome Source–Sink Mismatch
Every heartbeat originates from a tiny tissue in the heart called the sinoatrial node (SAN). The SAN harbors only ≈10 000 cardiac pacemaker cells, initiating an electrical impulse that captures the entire heart, consisting of billions of cardiomyocytes for each cardiac contraction. How these rare ca...
Autores principales: | Grijalva, Sandra I., Gu, Jin‐mo, Li, Jun, Fernandez, Natasha, Fan, Jinqi, Sung, Jung Hoon, Lee, Seung Yup, Herndon, Conner, Buckley, Erin M., Park, Sung‐Jin, Fenton, Flavio H., Cho, Hee Cheol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864514/ https://www.ncbi.nlm.nih.gov/pubmed/31763140 http://dx.doi.org/10.1002/advs.201901099 |
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