Multi-Target Chemometric Modelling, Fragment Analysis and Virtual Screening with ERK Inhibitors as Potential Anticancer Agents

Two isoforms of extracellular regulated kinase (ERK), namely ERK-1 and ERK-2, are associated with several cellular processes, the aberration of which leads to cancer. The ERK-1/2 inhibitors are thus considered as potential agents for cancer therapy. Multitarget quantitative structure–activity relati...

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Detalles Bibliográficos
Autores principales: Halder, Amit Kumar, Giri, Amal Kanta, Cordeiro, Maria Natália Dias Soeiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864583/
https://www.ncbi.nlm.nih.gov/pubmed/31671605
http://dx.doi.org/10.3390/molecules24213909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864583/
https://www.ncbi.nlm.nih.gov/pubmed/31671605
http://dx.doi.org/10.3390/molecules24213909

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