Immunotherapy: Janus Nanobullets Combine Photodynamic Therapy and Magnetic Hyperthermia to Potentiate Synergetic Anti‐Metastatic Immunotherapy (Adv. Sci. 22/2019)

In article number https://doi.org/10.1002/advs.201901690, Dan Shao, Wen Sun, Wen‐Fei Dong, and co‐workers report the development of Janus magnetic nanoparticles for redox/pH‐triggered photo‐sensitizer release with their matrix‐degradation behavior. Cancer cell membrane cloaking improves combined pho...

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Detalles Bibliográficos
Autores principales: Wang, Zheng, Zhang, Fan, Shao, Dan, Chang, Zhimin, Wang, Lei, Hu, Hanze, Zheng, Xiao, Li, Xuezhao, Chen, Fangman, Tu, Zhaoxu, Li, Mingqiang, Sun, Wen, Chen, Li, Dong, Wen‐Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864584/
http://dx.doi.org/10.1002/advs.201970136
Descripción
Sumario:In article number https://doi.org/10.1002/advs.201901690, Dan Shao, Wen Sun, Wen‐Fei Dong, and co‐workers report the development of Janus magnetic nanoparticles for redox/pH‐triggered photo‐sensitizer release with their matrix‐degradation behavior. Cancer cell membrane cloaking improves combined photodynamic therapy and magnetic hyperthermia in a remarkable anticancer manner, which is harnessed for a synergistic tumor‐specific immune response integrated with an anti‐cytotoxic T lymphocyte‐associated antigen‐4 anti‐body for notable eradication of primary and metastatic breast cancer with low systematic toxicity. [Image: see text]

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