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Artificial Blood: A Futuristic Dimension of Modern Day Transfusion Sciences
Artificial blood is an innovative concept of transfusion medicine where specifically designed compounds perform the task of transport and delivery of oxygen in the body to replace this function of allogenic human blood transfusion. Several molecules have been developed in the past few decades to ach...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Bentham Science Publishers
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864588/ https://www.ncbi.nlm.nih.gov/pubmed/31204626 http://dx.doi.org/10.2174/1871525717666190617120045 |
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author | Haldar, Rudrashish Gupta, Devendra Chitranshi, Shweta Singh, Manish Kumar Sachan, Sumit |
author_facet | Haldar, Rudrashish Gupta, Devendra Chitranshi, Shweta Singh, Manish Kumar Sachan, Sumit |
author_sort | Haldar, Rudrashish |
collection | PubMed |
description | Artificial blood is an innovative concept of transfusion medicine where specifically designed compounds perform the task of transport and delivery of oxygen in the body to replace this function of allogenic human blood transfusion. Several molecules have been developed in the past few decades to achieve this objective and continous refinements are being continuously made in the quest of the ideal blood substitute. Currently, available technology manufactures artificial blood from haemoglobin obtained from outdated human/bovine blood (Haemoglobin Based Oxygen Carriers) or utilizing Perfluorocarbons. These synthetic blood substitutes are advantageous in that they do not require compatibility testing, are free from blood borne infections, have prolonged shelf life and do not require refrigeration. Artificial blood is projected to have a significant impact on the development of medical care in the future. It can complement the current blood products for transfusion and create a stable supply of safe and effective products. It is likely to reduce the requirements of blood transfusions drastically especially in settings of trauma and surgery thereby reducing the reliance on banked donated blood. |
format | Online Article Text |
id | pubmed-6864588 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Bentham Science Publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-68645882020-01-02 Artificial Blood: A Futuristic Dimension of Modern Day Transfusion
Sciences Haldar, Rudrashish Gupta, Devendra Chitranshi, Shweta Singh, Manish Kumar Sachan, Sumit Cardiovasc Hematol Agents Med Chem Article Artificial blood is an innovative concept of transfusion medicine where specifically designed compounds perform the task of transport and delivery of oxygen in the body to replace this function of allogenic human blood transfusion. Several molecules have been developed in the past few decades to achieve this objective and continous refinements are being continuously made in the quest of the ideal blood substitute. Currently, available technology manufactures artificial blood from haemoglobin obtained from outdated human/bovine blood (Haemoglobin Based Oxygen Carriers) or utilizing Perfluorocarbons. These synthetic blood substitutes are advantageous in that they do not require compatibility testing, are free from blood borne infections, have prolonged shelf life and do not require refrigeration. Artificial blood is projected to have a significant impact on the development of medical care in the future. It can complement the current blood products for transfusion and create a stable supply of safe and effective products. It is likely to reduce the requirements of blood transfusions drastically especially in settings of trauma and surgery thereby reducing the reliance on banked donated blood. Bentham Science Publishers 2019-05 2019-05 /pmc/articles/PMC6864588/ /pubmed/31204626 http://dx.doi.org/10.2174/1871525717666190617120045 Text en © 2019 Bentham Science Publishers https://creativecommons.org/licenses/by-nc/4.0/legalcode This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited. |
spellingShingle | Article Haldar, Rudrashish Gupta, Devendra Chitranshi, Shweta Singh, Manish Kumar Sachan, Sumit Artificial Blood: A Futuristic Dimension of Modern Day Transfusion Sciences |
title | Artificial Blood: A Futuristic Dimension of Modern Day Transfusion
Sciences |
title_full | Artificial Blood: A Futuristic Dimension of Modern Day Transfusion
Sciences |
title_fullStr | Artificial Blood: A Futuristic Dimension of Modern Day Transfusion
Sciences |
title_full_unstemmed | Artificial Blood: A Futuristic Dimension of Modern Day Transfusion
Sciences |
title_short | Artificial Blood: A Futuristic Dimension of Modern Day Transfusion
Sciences |
title_sort | artificial blood: a futuristic dimension of modern day transfusion
sciences |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864588/ https://www.ncbi.nlm.nih.gov/pubmed/31204626 http://dx.doi.org/10.2174/1871525717666190617120045 |
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