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Artificial Blood: A Futuristic Dimension of Modern Day Transfusion 
Sciences

Artificial blood is an innovative concept of transfusion medicine where specifically designed compounds perform the task of transport and delivery of oxygen in the body to replace this function of allogenic human blood transfusion. Several molecules have been developed in the past few decades to ach...

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Autores principales: Haldar, Rudrashish, Gupta, Devendra, Chitranshi, Shweta, Singh, Manish Kumar, Sachan, Sumit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864588/
https://www.ncbi.nlm.nih.gov/pubmed/31204626
http://dx.doi.org/10.2174/1871525717666190617120045
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author Haldar, Rudrashish
Gupta, Devendra
Chitranshi, Shweta
Singh, Manish Kumar
Sachan, Sumit
author_facet Haldar, Rudrashish
Gupta, Devendra
Chitranshi, Shweta
Singh, Manish Kumar
Sachan, Sumit
author_sort Haldar, Rudrashish
collection PubMed
description Artificial blood is an innovative concept of transfusion medicine where specifically designed compounds perform the task of transport and delivery of oxygen in the body to replace this function of allogenic human blood transfusion. Several molecules have been developed in the past few decades to achieve this objective and continous refinements are being continuously made in the quest of the ideal blood substitute. Currently, available technology manufactures artificial blood from haemoglobin obtained from outdated human/bovine blood (Haemoglobin Based Oxygen Carriers) or utilizing Perfluorocarbons. These synthetic blood substitutes are advantageous in that they do not require compatibility testing, are free from blood borne infections, have prolonged shelf life and do not require refrigeration. Artificial blood is projected to have a significant impact on the development of medical care in the future. It can complement the current blood products for transfusion and create a stable supply of safe and effective products. It is likely to reduce the requirements of blood transfusions drastically especially in settings of trauma and surgery thereby reducing the reliance on banked donated blood.
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spelling pubmed-68645882020-01-02 Artificial Blood: A Futuristic Dimension of Modern Day Transfusion 
Sciences Haldar, Rudrashish Gupta, Devendra Chitranshi, Shweta Singh, Manish Kumar Sachan, Sumit Cardiovasc Hematol Agents Med Chem Article Artificial blood is an innovative concept of transfusion medicine where specifically designed compounds perform the task of transport and delivery of oxygen in the body to replace this function of allogenic human blood transfusion. Several molecules have been developed in the past few decades to achieve this objective and continous refinements are being continuously made in the quest of the ideal blood substitute. Currently, available technology manufactures artificial blood from haemoglobin obtained from outdated human/bovine blood (Haemoglobin Based Oxygen Carriers) or utilizing Perfluorocarbons. These synthetic blood substitutes are advantageous in that they do not require compatibility testing, are free from blood borne infections, have prolonged shelf life and do not require refrigeration. Artificial blood is projected to have a significant impact on the development of medical care in the future. It can complement the current blood products for transfusion and create a stable supply of safe and effective products. It is likely to reduce the requirements of blood transfusions drastically especially in settings of trauma and surgery thereby reducing the reliance on banked donated blood. Bentham Science Publishers 2019-05 2019-05 /pmc/articles/PMC6864588/ /pubmed/31204626 http://dx.doi.org/10.2174/1871525717666190617120045 Text en © 2019 Bentham Science Publishers https://creativecommons.org/licenses/by-nc/4.0/legalcode This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Haldar, Rudrashish
Gupta, Devendra
Chitranshi, Shweta
Singh, Manish Kumar
Sachan, Sumit
Artificial Blood: A Futuristic Dimension of Modern Day Transfusion 
Sciences
title Artificial Blood: A Futuristic Dimension of Modern Day Transfusion 
Sciences
title_full Artificial Blood: A Futuristic Dimension of Modern Day Transfusion 
Sciences
title_fullStr Artificial Blood: A Futuristic Dimension of Modern Day Transfusion 
Sciences
title_full_unstemmed Artificial Blood: A Futuristic Dimension of Modern Day Transfusion 
Sciences
title_short Artificial Blood: A Futuristic Dimension of Modern Day Transfusion 
Sciences
title_sort artificial blood: a futuristic dimension of modern day transfusion 
sciences
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864588/
https://www.ncbi.nlm.nih.gov/pubmed/31204626
http://dx.doi.org/10.2174/1871525717666190617120045
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