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Protective Effect of Edaravone on Cyclophosphamide Induced Oxidative Stress and Neurotoxicity in Rats

BACKGROUND: Cyclophosphamide (CPA) is the most widely prescribed cancer chemotherapeutic agent which shows serious neurotoxic side effect. Generation of reactive oxygen species at the cellular level is the basic mechanism of cyclophosphamide induced neurotoxicity. Edaravone is the synthetic drug use...

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Detalles Bibliográficos
Autores principales: Singh, Sanjiv, Kumar, Abhishek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864589/
https://www.ncbi.nlm.nih.gov/pubmed/31057112
http://dx.doi.org/10.2174/1574886314666190506100717