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Development and Validation of a Reporter-Cell-Line-Based Bioassay for Therapeutic Soluble gp130-Fc

Soluble glycoprotein 130 kDa (sgp130)-Fc fusion protein, an innovative therapeutic bio-macromolecular drug specifically targeting IL-6 trans-signaling, proved to have good potential for application in the treatment of chronic inflammatory diseases. A simple and quick bioassay for sgp130-Fc was devel...

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Detalles Bibliográficos
Autores principales: Yu, Lei, Jia, Chuncui, Yao, Wenrong, Pei, Dening, Qin, Xi, Rao, Chunming, Wang, Junzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864625/
https://www.ncbi.nlm.nih.gov/pubmed/31731431
http://dx.doi.org/10.3390/molecules24213845