Development and Validation of a Sensitive UHPLC-MS/MS Method for the Measurement of Gardneramine in Rat Plasma and Tissues and Its Application to Pharmacokinetics and Tissue Distribution Study

As a novel monoterpenoid indole alkaloid, gardneramine has been confirmed to possess excellent nervous depressive effects. However, there have been no reports about the measurement of gardneramine in vitro and in vivo. The motivation of this study was to establish and validate a specific, sensitive,...

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Detalles Bibliográficos
Autores principales: Zhao, Nan, Tan, Hao-ran, Chen, Qi-li, Sun, Qi, Wang, Lin, Song, Yang, Olounfeh, Kamara Mohamed, Meng, Fan-hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864695/
https://www.ncbi.nlm.nih.gov/pubmed/31683708
http://dx.doi.org/10.3390/molecules24213953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864695/
https://www.ncbi.nlm.nih.gov/pubmed/31683708
http://dx.doi.org/10.3390/molecules24213953

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