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Prediction of Severity of Drug-Drug Interactions Caused by Enzyme Inhibition and Activation

Drug-drug interactions (DDIs) severity assessment is a crucial problem because polypharmacy is increasingly common in modern medical practice. Many DDIs are caused by alterations of the plasma concentrations of one drug due to another drug inhibiting and/or inducing the metabolism or transporter-med...

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Detalles Bibliográficos
Autores principales:	Dmitriev, Alexander, Filimonov, Dmitry, Lagunin, Alexey, Karasev, Dmitry, Pogodin, Pavel, Rudik, Anastasiya, Poroikov, Vladimir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864873/ https://www.ncbi.nlm.nih.gov/pubmed/31683720 http://dx.doi.org/10.3390/molecules24213955

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