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Paradoxical clade- and age-specific vaccine effectiveness during the 2018/19 influenza A(H3N2) epidemic in Canada: potential imprint-regulated effect of vaccine (I-REV)

INTRODUCTION: The Canadian Sentinel Practitioner Surveillance Network reports vaccine effectiveness (VE) for the 2018/19 influenza A(H3N2) epidemic. AIM: To explain a paradoxical signal of increased clade 3C.3a risk among 35–54-year-old vaccinees, we hypothesise childhood immunological imprinting an...

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Autores principales:	Skowronski, Danuta M, Sabaiduc, Suzana, Leir, Siobhan, Rose, Caren, Zou, Macy, Murti, Michelle, Dickinson, James A, Olsha, Romy, Gubbay, Jonathan B, Croxen, Matthew A, Charest, Hugues, Bastien, Nathalie, Li, Yan, Jassem, Agatha, Krajden, Mel, De Serres, Gaston
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	European Centre for Disease Prevention and Control (ECDC) 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864978/ https://www.ncbi.nlm.nih.gov/pubmed/31771709 http://dx.doi.org/10.2807/1560-7917.ES.2019.24.46.1900585

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