Extracellular vesicles derived from human Wharton’s jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers

BACKGROUND: Mesenchymal stem cells (MSCs) have been explored as promising tools for treatment of several neurological and neurodegenerative diseases. MSCs release abundant extracellular vesicles (EVs) containing a variety of biomolecules, including mRNAs, miRNAs, and proteins. We hypothesized that E...

Descripción completa

Detalles Bibliográficos
Autores principales: Bodart-Santos, Victor, de Carvalho, Luiza R. P., de Godoy, Mariana A., Batista, André F., Saraiva, Leonardo M., Lima, Luize G., Abreu, Carla Andreia, De Felice, Fernanda G., Galina, Antonio, Mendez-Otero, Rosalia, Ferreira, Sergio T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864996/
https://www.ncbi.nlm.nih.gov/pubmed/31747944
http://dx.doi.org/10.1186/s13287-019-1432-5

Ejemplares similares

Ejemplares similares