Significant Weight Loss in a Patient Taking Olmesartan: An Unusual Case Report

OBJECTIVE: Olmesartan-induced enteropathy consists a syndrome that mimics celiac disease both clinically and histologically. Cases of this entity have sporadically been reported since 2012 and are usually characterized by severe diarrhea and malabsorption, followed by significant weight loss. CASE R...

Descripción completa

Detalles Bibliográficos
Autores principales: Makri, Andromachi, Florentin, Matilda, Elisaf, Moses S., Liamis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865051/
https://www.ncbi.nlm.nih.gov/pubmed/30848210
http://dx.doi.org/10.2174/1574886314666190307142111
_version_ 1783472018836946944
author Makri, Andromachi
Florentin, Matilda
Elisaf, Moses S.
Liamis, George
author_facet Makri, Andromachi
Florentin, Matilda
Elisaf, Moses S.
Liamis, George
author_sort Makri, Andromachi
collection PubMed
description OBJECTIVE: Olmesartan-induced enteropathy consists a syndrome that mimics celiac disease both clinically and histologically. Cases of this entity have sporadically been reported since 2012 and are usually characterized by severe diarrhea and malabsorption, followed by significant weight loss. CASE REPORT: Herein, we report an uncommon case of this syndrome, where weight loss preceded several months the onset of gastrointestinal symptoms. DISCUSSION AND CONCLUSION: Physicians should be aware of unexplained weight loss in patients taking olmesartan, as prompt discontinuation of the drug may prevent the deleterious consequences of malabsorption.
format Online
Article
Text
id pubmed-6865051
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Bentham Science Publishers
record_format MEDLINE/PubMed
spelling pubmed-68650512020-01-02 Significant Weight Loss in a Patient Taking Olmesartan: An Unusual Case Report Makri, Andromachi Florentin, Matilda Elisaf, Moses S. Liamis, George Curr Drug Saf Article OBJECTIVE: Olmesartan-induced enteropathy consists a syndrome that mimics celiac disease both clinically and histologically. Cases of this entity have sporadically been reported since 2012 and are usually characterized by severe diarrhea and malabsorption, followed by significant weight loss. CASE REPORT: Herein, we report an uncommon case of this syndrome, where weight loss preceded several months the onset of gastrointestinal symptoms. DISCUSSION AND CONCLUSION: Physicians should be aware of unexplained weight loss in patients taking olmesartan, as prompt discontinuation of the drug may prevent the deleterious consequences of malabsorption. Bentham Science Publishers 2019-11 2019-11 /pmc/articles/PMC6865051/ /pubmed/30848210 http://dx.doi.org/10.2174/1574886314666190307142111 Text en © 2019 Bentham Science Publishers https://creativecommons.org/licenses/by-nc/4.0/legalcode This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Makri, Andromachi
Florentin, Matilda
Elisaf, Moses S.
Liamis, George
Significant Weight Loss in a Patient Taking Olmesartan: An Unusual Case Report
title Significant Weight Loss in a Patient Taking Olmesartan: An Unusual Case Report
title_full Significant Weight Loss in a Patient Taking Olmesartan: An Unusual Case Report
title_fullStr Significant Weight Loss in a Patient Taking Olmesartan: An Unusual Case Report
title_full_unstemmed Significant Weight Loss in a Patient Taking Olmesartan: An Unusual Case Report
title_short Significant Weight Loss in a Patient Taking Olmesartan: An Unusual Case Report
title_sort significant weight loss in a patient taking olmesartan: an unusual case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865051/
https://www.ncbi.nlm.nih.gov/pubmed/30848210
http://dx.doi.org/10.2174/1574886314666190307142111
work_keys_str_mv AT makriandromachi significantweightlossinapatienttakingolmesartananunusualcasereport
AT florentinmatilda significantweightlossinapatienttakingolmesartananunusualcasereport
AT elisafmosess significantweightlossinapatienttakingolmesartananunusualcasereport
AT liamisgeorge significantweightlossinapatienttakingolmesartananunusualcasereport

Ejemplares similares