Cargando…
Whole-genome fetal and maternal DNA methylation analysis using MeDIP-NGS for the identification of differentially methylated regions
DNA methylation is an epigenetic marker that has been shown to vary significantly across different tissues. Taking advantage of the methylation differences between placenta-derived cell-free DNA and maternal blood, several groups employed different approaches for the discovery of fetal-specific biom...
Autores principales: | KERAVNOU, ANNA, IOANNIDES, MARIOS, TSANGARAS, KYRIAKOS, LOIZIDES, CHARALAMBOS, HADJIDANIEL, MICHAEL D., PAPAGEORGIOU, ELISAVET A., KYRIAKOU, SKEVI, ANTONIOU, PAVLOS, MINA, PETROS, ACHILLEOS, ACHILLEAS, NEOFYTOU, MARIA, KYPRI, ELENA, SISMANI, CAROLINA, KOUMBARIS, GEORGE, PATSALIS, PHILIPPOS C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865150/ https://www.ncbi.nlm.nih.gov/pubmed/27834155 http://dx.doi.org/10.1017/S0016672316000136 |
Ejemplares similares
-
MeDIP combined with in-solution targeted enrichment followed by NGS: Inter-individual methylation variability of fetal-specific biomarkers and their implementation in a proof of concept study for NIPT
por: Keravnou, Anna, et al.
Publicado: (2018) -
Development of a new methylation‐based fetal fraction estimation assay using multiplex ddPCR
por: Ioannides, Marios, et al.
Publicado: (2019) -
Targeted capture enrichment assay for non-invasive prenatal testing of large and small size sub-chromosomal deletions and duplications
por: Neofytou, Maria C., et al.
Publicado: (2017) -
Inter-individual methylation variability in differentially methylated regions between maternal whole blood and first trimester CVS
por: Ioannides, Marios, et al.
Publicado: (2014) -
Targeted capture enrichment followed by NGS: development and validation of a single comprehensive NIPT for chromosomal aneuploidies, microdeletion syndromes and monogenic diseases
por: Koumbaris, George, et al.
Publicado: (2019)