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Exploring the Conformational Space of Bcl-2 Protein Variants: Dynamic Contributions of the Flexible Loop Domain and Transmembrane Region

Members of the Bcl-2 protein family regulate apoptosis through interactions with several proteins. A critical intrinsically disordered region (IDR) present in some members of the Bcl-2 family is essential for their function. Also, the structural and conformational plasticity of disordered regions is...

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Detalles Bibliográficos
Autores principales:	Caro-Gómez, Luis A., Rosas-Trigueros, Jorge L., Mixcoha, Edgar, Vique-Sánchez, José L., Gasperin-Sánchez, Humberto, Benítez-Cardoza, Claudia G., Zamorano-Carrillo, Absalom
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865210/ https://www.ncbi.nlm.nih.gov/pubmed/31671865 http://dx.doi.org/10.3390/molecules24213896

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