Elevated Uric Acid Levels Promote Vascular Smooth Muscle Cells (VSMC) Proliferation via an Nod-Like Receptor Protein 3 (NLRP3)-Inflammasome-Dependent Mechanism

BACKGROUND: Hyperuricemia has a pathogenic role in the development of hypertension and other cardiovascular diseases (CVD). Uric acid has been reported to activate Nod-like receptor protein 3 (NLRP3)-inflammasome and alter vascular smooth muscle cells (VSMC). However, the potential mechanisms underl...

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Detalles Bibliográficos
Autores principales: Li, Hui, Qian, Fudong, Liu, Heyu, Zhang, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865250/
https://www.ncbi.nlm.nih.gov/pubmed/31707403
http://dx.doi.org/10.12659/MSM.916667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865250/
https://www.ncbi.nlm.nih.gov/pubmed/31707403
http://dx.doi.org/10.12659/MSM.916667

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