Cargando…
An Integrated Model of Minor Intron Emergence and Conservation
Minor introns constitute <0.5% of the introns in the human genome and have remained an enigma since their discovery. These introns are removed by a distinct splicing complex, the minor spliceosome. Both are ancient, tracing back to the last eukaryotic common ancestor (LECA), which is reflected by...
Autores principales: | Baumgartner, Marybeth, Drake, Kyle, Kanadia, Rahul N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865273/ https://www.ncbi.nlm.nih.gov/pubmed/31798628 http://dx.doi.org/10.3389/fgene.2019.01113 |
Ejemplares similares
-
Minor intron splicing revisited: identification of new minor intron-containing genes and tissue-dependent retention and alternative splicing of minor introns
por: Olthof, Anouk M., et al.
Publicado: (2019) -
Introns: the “dark matter” of the eukaryotic genome
por: Girardini, Kaitlin N., et al.
Publicado: (2023) -
Disrupted minor intron splicing is prevalent in Mendelian disorders
por: Olthof, Anouk M., et al.
Publicado: (2020) -
Role of NDE1 in the Development and Evolution of the Gyrified Cortex
por: Soto-Perez, Jaseph, et al.
Publicado: (2020) -
Disruption of exon-bridging interactions between the minor and major spliceosomes results in alternative splicing around minor introns
por: Olthof, Anouk M, et al.
Publicado: (2021)