Cargando…

Cyclin-dependent kinase 9 expression and its association with CD8(+) T cell infiltration in microsatellite-stable colorectal cancer

Programmed death 1 (PD-1)-targeted therapy has benefited patients with microsatellite instability-high metastatic colorectal cancer (mCRC). However, the efficacy of PD-1-targeted therapy is poor in patients with microsatellite-stable (MSS) mCRC. Therefore, it is imperative to explore additional co-i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jiefu, Liu, Jia, Tian, Fei, Zhan, Yang, Kong, Dalu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865572/ https://www.ncbi.nlm.nih.gov/pubmed/31788079 http://dx.doi.org/10.3892/ol.2019.10970

Ejemplares similares

Down-regulating cyclin-dependent kinase 9 of alloreactive CD4(+) T cells prolongs allograft survival
por: Zhan, Yang, et al.
Publicado: (2016)

Expression of cyclin-dependent kinases and their clinical significance with immune infiltrates could predict prognosis in colorectal cancer
por: Fadaka, Adewale Oluwaseun, et al.
Publicado: (2021)

Influence of Race on Microsatellite Instability and CD8(+) T Cell Infiltration in Colon Cancer
por: Carethers, John M., et al.
Publicado: (2014)

Lymphocytic infiltration in stage II microsatellite stable colorectal tumors: A retrospective prognosis biomarker analysis
por: Sanz-Pamplona, Rebeca, et al.
Publicado: (2020)

Correction: Influence of Race on Microsatellite Instability and CD8(+) T Cell Infiltration in Colon Cancer
Publicado: (2014)

Differential expression of DHHC9 in microsatellite stable and instable human colorectal cancer subgroups
por: Mansilla, F, et al.
Publicado: (2007)

CD3(+) and CD8(+) T-Cell-Based Immune Cell Score and PD-(L)1 Expression in Pulmonary Metastases of Microsatellite Stable Colorectal Cancer
por: Karjula, Topias, et al.
Publicado: (2022)

The expressed mutational landscape of microsatellite stable colorectal cancers
por: Sveen, Anita, et al.
Publicado: (2021)

Effects of Cyclin Dependent Kinase 9 inhibition on zebrafish larvae
por: Matrone, Gianfranco, et al.
Publicado: (2016)

Cyclin Dependent Kinase 9 Inhibitors for Cancer Therapy: Miniperspective
por: Sonawane, Yogesh A., et al.
Publicado: (2016)

Beyond Microsatellite Instability: Evolving Strategies Integrating Immunotherapy for Microsatellite Stable Colorectal Cancer
por: Pecci, Federica, et al.
Publicado: (2021)

Perspective of Cyclin-dependent kinase 9 (CDK9) as a Drug Target
por: Kryštof, Vladimír, et al.
Publicado: (2012)

Tumor-Infiltrating Lymphoid Cells in Colorectal Cancer Patients with Varying Disease Stages and Microsatellite Instability-High/Stable Tumors
por: Toor, Salman M., et al.
Publicado: (2021)

mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC)
por: Feng, Daorong, et al.
Publicado: (2015)

Cyclin-dependent kinases
por: Malumbres, Marcos
Publicado: (2014)

SnoN expression is differently regulated in microsatellite unstable compared with microsatellite stable colorectal cancers
por: Chia, June A, et al.
Publicado: (2006)

Chromosomal Instability in BRAF Mutant, Microsatellite Stable Colorectal Cancers
por: Bond, Catherine E., et al.
Publicado: (2012)

Is There a Place for Immunotherapy for Metastatic Microsatellite Stable Colorectal Cancer?
por: Ghiringhelli, François, et al.
Publicado: (2019)

The Emerging Role of Checkpoint Inhibition in Microsatellite Stable Colorectal Cancer
por: Hermel, David J., et al.
Publicado: (2019)

Cyclin-Dependent Kinase 9 Activity Regulates Neutrophil Spontaneous Apoptosis
por: Wang, Keqing, et al.
Publicado: (2012)

Antitumor effects of cyclin dependent kinase 9 inhibition in esophageal adenocarcinoma
por: Tong, Zhimin, et al.
Publicado: (2017)

Small molecule inhibitors of cyclin-dependent kinase 9 for cancer therapy
por: Alsfouk, Aisha
Publicado: (2021)

Adapalene inhibits the activity of cyclin-dependent kinase 2 in colorectal carcinoma
por: SHI, XI-NAN, et al.
Publicado: (2015)

Cyclin-Dependent Kinase Inhibitors and Their Therapeutic Potential in Colorectal Cancer Treatment
por: Thoma, Oana-Maria, et al.
Publicado: (2021)

Pharmacokinetics and biodistribution of the cyclin-dependent kinase inhibitor -CR8- in mice
por: Sallam, Hatem, et al.
Publicado: (2013)

Identification of novel inhibitors against Cyclin Dependent Kinase 9/Cyclin T1 complex as: Anti cancer agent
por: Hussain, Afzal, et al.
Publicado: (2017)

Identification of a Subset of Microsatellite-Stable Endometrial Carcinoma with High PD-L1 and CD8+ Lymphocytes
por: Crumley, Suzanne, et al.
Publicado: (2018)

The Impact of Tumor Cell-Intrinsic Expression of Cyclic GMP-AMP Synthase (cGAS)-Stimulator of Interferon Genes (STING) on the Infiltration of CD8(+) T Cells and Clinical Outcomes in Mismatch Repair Proficient/Microsatellite Stable Colorectal Cancer
por: Nakajima, Shotaro, et al.
Publicado: (2023)

Long noncoding RNA LINC01578 drives colon cancer metastasis through a positive feedback loop with the NF‐κB/YY1 axis
por: Liu, Jia, et al.
Publicado: (2020)

Co-inhibitor expression on tumor infiltrating and splenic lymphocytes after dual checkpoint inhibition in a microsatellite stable model of colorectal cancer
por: Slovak, Ryan J., et al.
Publicado: (2021)

The Regulation of Cyclins and Cyclin-Dependent Kinases in the Development of Gastric Cancer
por: Javed, Aadil, et al.
Publicado: (2023)

Functional Differentiation of Cyclins and Cyclin-Dependent Kinases in Giardia lamblia
por: Kim, Juri, et al.
Publicado: (2023)

Serum cyclin-dependent kinase 9 is a potential biomarker of atherosclerotic inflammation
por: Han, Yeming, et al.
Publicado: (2015)

The anti‐human cytomegalovirus drug tricin inhibits cyclin‐dependent kinase 9
por: Sadanari, Hidetaka, et al.
Publicado: (2018)

Cyclin-dependent kinase 9 is required for the survival of adult Drosophila melanogaster glia
por: Foo, Lynette C.
Publicado: (2017)

MBRS-67. ROLE OF CYCLIN DEPENDENT KINASE-9 IN Myc-ENHANCED MEDULLOBLASTOMA
por: Madhavan, Krishna, et al.
Publicado: (2020)

Transcriptome and Network Dissection of Microsatellite Stable and Highly Instable Colorectal Cancer
por: Akbari, Vahid, et al.
Publicado: (2019)

Tertiary lymphoid structures in pulmonary metastases of microsatellite stable colorectal cancer
por: Karjula, Topias, et al.
Publicado: (2023)

Chemoimmunotherapy triggers immune responses targeting microsatellite stable colorectal cancer
por: Thibaudin, Marion, et al.
Publicado: (2023)

Editorial: New therapeutic approaches in microsatellite stable colorectal cancer patients
por: Bartolini, Michela, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_90267k8b12ok9v3cnsv5rkcgga