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Functional impact of the long non-coding RNA MEG3 deletion by CRISPR/Cas9 in the human triple negative metastatic Hs578T cancer cell line

Long non-coding RNAs (lncRNAs) serve critical roles in regulating cellular homeostasis, and their deregulated expression/activity is associated with neoplastic transformation. The maternally expressed gene 3 (MEG3) has been extensively described as a tumor suppressor gene in different types of cance...

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Detalles Bibliográficos
Autores principales:	Deocesano-Pereira, Carlos, Machado, Raquel Arminda Carvalho, De Jesus-Ferreira, Henrique Cesar, Marchini, Thiago, Pereira, Tulio Felipe, Carreira, Ana Claudia Oliveira, Sogayar, Mari Cleide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865607/ https://www.ncbi.nlm.nih.gov/pubmed/31788068 http://dx.doi.org/10.3892/ol.2019.10969

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