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Mutant-allele tumor heterogeneity in malignant glioma effectively predicts neoplastic recurrence
Intra-tumor heterogeneity (ITH) is one of the most important causes of therapy resistance, which eventually leads to the poor outcomes observed in patients with glioma. Mutant-allele tumor heterogeneity (MATH) values are based on whole-exon sequencing and precisely reflect genetic ITH. However, the...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865645/ https://www.ncbi.nlm.nih.gov/pubmed/31788085 http://dx.doi.org/10.3892/ol.2019.10978 |